Influence of KRAS Mutation Status in Metachronous and Synchronous Metastatic Colorectal Adenocarcinoma

BACKGROUND: Mutations in the v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) are present in approximately 30% to 40% of colorectal adenocarcinomas. Wild-type (WT) KRAS mutation status is predictive of tumor response with epidermal growth factor receptor-directed therapies, but the result...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rose, Jeffrey S., Serna, Derek S., Martin, Ludmila Katherine, Li, Xiaobai, Weatherby, Lynn M., Abdel-Misih, Sherif, Zhao, Weiqiang, Bekaii-Saab, Tanios
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839285/
https://ncbi.nlm.nih.gov/pubmed/22674181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27666
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