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Quantifying Lead-Time Bias in Risk-Factor Studies of Cancer through Simulation
PURPOSE: Lead-time is inherent in early detection and creates bias in observational studies of screening efficacy, but its potential to bias effect estimates in risk-factor studies is not always recognized. We describe a form of this bias that conventional analyses cannot address and develop a model...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839248/ https://ncbi.nlm.nih.gov/pubmed/23988688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annepidem.2013.07.021 |
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