Cell-free synthesis and segregation of beta 2-microglobulin.

beta2-Microglobulin has been synthesized in vitro by using a rabbit reticulocyte lysate system and mRNA from the mouse tumor cell line EL4. The molecule is synthesized as a precursor with an NH2-terminal extension of 19 amino acids: Ser-X-Ser-Val-X-Leu-Val-Phe-Leu-Val-Leu-Val-Ser-Leu-X-Gly-Leu-Tyr-X...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Lingappa, V R, Cunningham, B A, Jazwinski, S M, Hopp, T P, Blobel, G, Edelman, G M
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1979
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/91168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3651
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