Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes.

UV irradiation interferes with the induction of T cell-mediated immune responses, in part by causing cells in the skin to produce immunoregulatory cytokines. Recent evidence implicates UV-induced DNA damage as a trigger for the cascade of events leading to systemic immune suppression in vivo. Howeve...

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Main Authors: Nishigori, C, Yarosh, D B, Ullrich, S E, Vink, A A, Bucana, C D, Roza, L, Kripke, M L
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38388/
https://ncbi.nlm.nih.gov/pubmed/8816804
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