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Apc Deficiency Alters Pulmonary Epithelial Cell Fate and Inhibits Nkx2.1 via Triggering TGF-beta Signaling

Wnt signaling is critical for cell fate specification and cell differentiation in many organs, but its function in pulmonary neuroendocrine cell (PNEC) differentiation has not been fully addressed. In this study, we examined the role of canonical Wnt signaling by targeting the gene for Adenomatous P...

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Hlavní autoři: Li, Changgong, Li, Aimin, Xing, Yiming, Li, Min, Chan, Belinda, Ouyang, Ruoyun, Taketo, Makoto Mark, Kucherlapati, Raju, Borok, Zea, Minoo, Parviz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838671/
https://ncbi.nlm.nih.gov/pubmed/23562608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.03.018
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