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Immunohistochemical and ultrastructural features of congenital melanocytic naevus cells support a stem-cell phenotype

Background Multiple congenital melanocytic naevi (CMN) in one individual are caused by somatic mosaicism for NRAS mutations; however, the lineage of the mutated cells remains uncertain. Objectives To test the hypothesis that CMN may be derived from cutaneous stem cells. Methods Sixty-six CMN samples...

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Detalhes bibliográficos
Main Authors: Kinsler, VA, Anderson, G, Latimer, B, Natarajan, D, Healy, E, Moore, GE, Sebire, NJ
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838625/
https://ncbi.nlm.nih.gov/pubmed/23517330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjd.12323
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