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Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target
Mycobacterium tuberculosis (Mtb) acquires non-heme iron through salicylate-derived siderophores termed mycobactins whereas heme iron is obtained through a cascade of heme uptake proteins. Three proteins are proposed to mediate Mtb heme iron uptake, a secreted heme transporter (Rv0203), and MmpL3 and...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838433/ https://ncbi.nlm.nih.gov/pubmed/23919550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.109 |
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