Extended Duration of Transgene Expression from Pegylated POD Nanoparticles Enables Attenuation of Photoreceptor Degeneration

Retinitis pigmentosa (RP) is the most genetically heterogeneous disorder known to cause blindness, involving over 50 different genes. Previously, we have described nanoparticles (NPs) 150 nm in size, comprised of a 3.5 kD peptide (POD) complexed to PEG and DNA (PEGPOD DNA). These NPs expressing GDNF...

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Detaylı Bibliyografya
Asıl Yazarlar: Binder, Christina, Cashman, Siobhan M., Kumar-Singh, Rajendra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838409/
https://ncbi.nlm.nih.gov/pubmed/24278479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082295
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