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Comprehensive Analysis of Human Endogenous Retrovirus Group HERV-W Locus Transcription in Multiple Sclerosis Brain Lesions by High-Throughput Amplicon Sequencing

Human endogenous retroviruses (HERVs) of the HERV-W group comprise hundreds of loci in the human genome. Deregulated HERV-W expression and HERV-W locus ERVWE1-encoded Syncytin-1 protein have been implicated in the pathogenesis of multiple sclerosis (MS). However, the actual transcription of HERV-W l...

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書誌詳細
主要な著者: Schmitt, Katja, Richter, Christin, Backes, Christina, Meese, Eckart, Ruprecht, Klemens, Mayer, Jens
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838257/
https://ncbi.nlm.nih.gov/pubmed/24109235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02388-13
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