Deep-Sequencing Analysis of the Association between the Quasispecies Nature of the Hepatitis C Virus Core Region and Disease Progression

Variation of core amino acid (aa) 70 of hepatitis C virus (HCV) has been shown recently to be closely correlated with liver disease progression, suggesting that the core region might be present as a quasispecies during persistent infection and that this quasispecies nature might have an influence on...

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Autores principales: Miura, Mika, Maekawa, Shinya, Takano, Shinichi, Komatsu, Nobutoshi, Tatsumi, Akihisa, Asakawa, Yukiko, Shindo, Kuniaki, Amemiya, Fumitake, Nakayama, Yasuhiro, Inoue, Taisuke, Sakamoto, Minoru, Yamashita, Atsuya, Moriishi, Kohji, Enomoto, Nobuyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838162/
https://ncbi.nlm.nih.gov/pubmed/23946458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00826-13
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