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A C-Terminal Acidic Domain Regulates Degradation of the Transcriptional Coactivator Bob1
Bob1 (Obf-1 or OCA-B) is a 34-kDa transcriptional coactivator encoded by the Pou2af1 gene that is essential for normal B-cell development and immune responses in mice. During lymphocyte activation, Bob1 protein levels dramatically increase independently of mRNA levels, suggesting that the stability...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838006/ https://ncbi.nlm.nih.gov/pubmed/24061476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01590-12 |
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