CD4(+) T Cells Drive Goblet Cell Depletion during Citrobacter rodentium Infection

Both idiopathic and infectious forms of colitis disrupt normal intestinal epithelial cell (IEC) proliferation and differentiation, although the mechanisms involved remain unclear. Recently, we demonstrated that infection by the attaching and effacing murine pathogen Citrobacter rodentium leads to a...

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Bibliographic Details
Main Authors: Chan, Justin M., Bhinder, Ganive, Sham, Ho Pan, Ryz, Natasha, Huang, Tina, Bergstrom, Kirk S., Vallance, Bruce A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837981/
https://ncbi.nlm.nih.gov/pubmed/24101690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00655-13
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