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Trimeric Autotransporter DsrA Is a Major Mediator of Fibrinogen Binding in Haemophilus ducreyi

Haemophilus ducreyi is the etiologic agent of the sexually transmitted genital ulcer disease chancroid. In both natural and experimental chancroid, H. ducreyi colocalizes with fibrin at the base of the ulcer. Fibrin is obtained by cleavage of the serum glycoprotein fibrinogen (Fg) by thrombin to ini...

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Библиографические подробности
Главные авторы: Fusco, William G., Elkins, Christopher, Leduc, Isabelle
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837977/
https://ncbi.nlm.nih.gov/pubmed/24042118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00743-13
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