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Restricted Substrate Specificity for the Geranylgeranyltransferase-I Enzyme in Cryptococcus neoformans: Implications for Virulence

Proper cellular localization is required for the function of many proteins. The CaaX prenyltransferases (where CaaX indicates a cysteine followed by two aliphatic amino acids and a variable amino acid) direct the subcellular localization of a large group of proteins by catalyzing the attachment of h...

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Autors principals: Selvig, Kyla, Ballou, Elizabeth R., Nichols, Connie B., Alspaugh, J. Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837929/
https://ncbi.nlm.nih.gov/pubmed/24014765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00193-13
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