Activity of Tigecycline in Combination with Colistin, Meropenem, Rifampin, or Gentamicin against KPC-Producing Enterobacteriaceae in a Murine Thigh Infection Model

Limited antimicrobials remain active for treating severe infections due to KPC-producing pathogens, and optimal regimens have not been established. In murine thigh infections caused by nine KPC-producing clinical strains of Enterobacteriaceae (meropenem MICs, 1 to 4 μg/ml), we evaluated the activiti...

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Hlavní autoři: Michail, George, Labrou, Maria, Pitiriga, Vassiliki, Manousaka, Styliani, Sakellaridis, Nikolaos, Tsakris, Athanasios, Pournaras, Spyros
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837854/
https://ncbi.nlm.nih.gov/pubmed/24060874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00891-13
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