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Isavuconazole (BAL4815) Pharmacodynamic Target Determination in an In Vivo Murine Model of Invasive Pulmonary Aspergillosis against Wild-Type and cyp51 Mutant Isolates of Aspergillus fumigatus

Invasive pulmonary aspergillosis (IPA) continues to rise in concert with increasing numbers of immune suppression techniques to treat other medical conditions and transplantation. Despite these advances, morbidity and mortality rates remain unacceptably high. One strategy used to optimize outcomes i...

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書誌詳細
主要な著者: Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Andes, David R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837846/
https://ncbi.nlm.nih.gov/pubmed/24100500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01355-13
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