ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-α

Metalloproteinases are implicated in cleaving numerous pro-inflammatory mediators from the cell surface. Interestingly, elevated levels of TNF-α have been associated with the metabolic syndrome. We aimed to ascertain whether the human metalloproteinase ADAM28 correlates with parameters of the metabo...

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Main Authors: Jowett, Jeremy B. M., Okada, Yasunori, Leedman, Peter J., Curran, Joanne E., Johnson, Matthew P., Moses, Eric K., Goring, Harald H.H., Mochizuki, Satsuki, Blangero, John, Stone, Leah, Allen, Holly, Mitchell, Chris, Matthews, Vance B.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837706/
https://ncbi.nlm.nih.gov/pubmed/23010875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2012.44
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