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Imaging of Superoxide Generation in the Dopaminergic Area of the Brain in Parkinson’s Disease, Using Mito-TEMPO

[Image: see text] We report a new methodology for direct visualization of superoxide production in the dopaminergic area of the brain in Parkinson’s disease, based on the redox cycle of mito-TEMPO, a blood-brain barrier-, cell-, and mitochondria-penetrating nitroxide derivative with superoxide scave...

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Detalhes bibliográficos
Main Authors: Zhelev, Zhivko, Bakalova, Rumiana, Aoki, Ichio, Lazarova, Dessislava, Saga, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837371/
https://ncbi.nlm.nih.gov/pubmed/24024751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400159h
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