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Aberrant Crypt Foci: The Case for Inclusion as a Biomarker for Colon Cancer

Aberrant crypt foci (ACF) are one of the earliest histopathological manifestations of colon cancer. In this review, we critically present the molecular, cellular, histopathological, and chemopreventive evidence that ACF are relevant biomarkers for colon cancer. The laboratory and clinical evidence a...

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Detalhes bibliográficos
Main Authors: Wargovich, Michael J., Brown, Vondina R., Morris, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837333/
https://ncbi.nlm.nih.gov/pubmed/24281183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers2031705
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