Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles

The construction of nanostructures from biodegradable precursors and shell/core crosslinking have been pursued as strategies to solve the problems of toxicity and limited stability, respectively. Polyphosphoester (PPE)-based micelles and crosslinked nanoparticles with non-ionic, anionic, cationic, a...

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Detalhes bibliográficos
Main Authors: Elsabahy, Mahmoud, Zhang, Shiyi, Zhang, Fuwu, Deng, Zhou J., Lim, Young H., Wang, Hai, Parsamian, Perouza, Hammond, Paula T., Wooley, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837308/
https://ncbi.nlm.nih.gov/pubmed/24264796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03313
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