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Safety Evaluation of Combination Vinblastine and Toceranib Phosphate (Palladia®) in Dogs: a Phase I dose-finding study

Combining drugs with known single-agent activity that lack overlapping dose-limiting toxicities and exert antitumor activity through different mechanisms could improve clinical outcome. As toceranib and vinblastine meet these requisites, a phase I trial was performed on the combination in dogs with...

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Detalhes bibliográficos
Main Authors: Robat, Cecilia, London, Cheryl, Bunting, Lyndsay, McCartan, Lassara, Stingle, Nicole, Selting, Kim, Kurzman, Ilene, Vail, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837095/
https://ncbi.nlm.nih.gov/pubmed/22235914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5829.2011.00261.x
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