Vascular Endothelial Growth Factor-A and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets

Pancreatic islets are highly vascularized mini-organs, and vascular endothelial growth factor (VEGF)-A is a critical factor in the development of islet vascularization. To investigate the role of VEGF-A and endothelial cells (ECs) in adult islets, we used complementary genetic approaches to temporal...

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Autori principali: Reinert, Rachel B., Brissova, Marcela, Shostak, Alena, Pan, Fong Cheng, Poffenberger, Greg, Cai, Qing, Hundemer, Gregory L., Kantz, Jeannelle, Thompson, Courtney S., Dai, Chunhua, McGuinness, Owen P., Powers, Alvin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837071/
https://ncbi.nlm.nih.gov/pubmed/23884891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0071
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