Llwytho...

Demonstration of low density lipoprotein receptors in mouse teratocarcinoma stem cells and description of a method for producing receptor-deficient mutant mice

Familial hypercholesterolemia, a widespread human genetic disorder implicated in vascular and coronary disease, has had no laboratory animal counterpart that would enable the pathogenesis to be analyzed and drugs to be tested in vivo. The primary lesion in some patients is known to occur in the cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Goldstein, Joseph L., Brown, Michael S., Krieger, Monty, Anderson, Richard G. W., Mintz, Beatrice
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1979
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383705/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/223161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2843
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