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Non-Invasive In Vivo Imaging of Near Infrared-labeled Transferrin in Breast Cancer Cells and Tumors Using Fluorescence Lifetime FRET

The conjugation of anti-cancer drugs to endogenous ligands has proven to be an effective strategy to enhance their pharmacological selectivity and delivery towards neoplasic tissues. Since cell proliferation has a strong requirement for iron, cancer cells express high levels of transferrin receptors...

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Detalhes bibliográficos
Main Authors: Abe, Ken, Zhao, Lingling, Periasamy, Ammasi, Intes, Xavier, Barroso, Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836976/
https://ncbi.nlm.nih.gov/pubmed/24278268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080269
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