A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches

Painful degenerative disc diseases have been targeted by different biological treatment approaches. Nucleus pulposus (NP) cells play a central role in intervertebral disc (IVD) maintenance by orchestrating catabolic, anabolic and inflammatory factors that affect the extracellular matrix. IVD degener...

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Main Authors: Mern, Demissew S., Fontana, Johann, Beierfuß, Anja, Thomé, Claudius, Hegewald, Aldemar A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836971/
https://ncbi.nlm.nih.gov/pubmed/24278441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081467
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