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Comparison of HER2 and Phospho-HER2 Expression between Biopsy and Resected Breast Cancer Specimens Using a Quantitative Assessment Method

BACKGROUND: HER2/Neu (ErbB-2) overexpression, which occurs in 15–20% of breast cancer cases, is associated with better response to treatment with the drug trastuzumab. PhosphoHER2 (pHER2) has been evaluated for prediction of response to trastuzumab. Both markers are heterogeneously detected and are...

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Autori principali: Bai, Yalai, Cheng, Huan, Bordeaux, Jennifer, Neumeister, Veronique, Kumar, Sudha, Rimm, David L., Stern, David F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836903/
https://ncbi.nlm.nih.gov/pubmed/24278211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079901
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