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Malaria’s Deadly Grip: Cytoadhesion of Plasmodium falciparum Infected Erythrocytes

Cytoadhesion of Plasmodium falciparum infected erythrocytes to host microvasculature is a key virulence determinant. Parasite binding is mediated by a large family of clonally variant adhesion proteins, termed P. falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by var genes and expressed...

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Bibliographic Details
Main Authors: Smith, Joseph D., Rowe, J. Alexandra, Higgins, Matthew K., Lavstsen, Thomas
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836831/
https://ncbi.nlm.nih.gov/pubmed/23957661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12183
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