Formalin-Inactivated EV71 Vaccine Candidate Induced Cross-Neutralizing Antibody against Subgenotypes B1, B4, B5 and C4A in Adult Volunteers

BACKGROUND: Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open-label phase I clinical study registered with ClinicalTrials.gov #NCT01268787, aims to evaluate the safety, reactogenicity and...

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Detalhes bibliográficos
Main Authors: Chou, Ai-Hsiang, Liu, Chia-Chyi, Chang, Jui-Yuan, Jiang, Renee, Hsieh, Yi-Chin, Tsao, Amanda, Wu, Chien-Long, Huang, Ju-Lan, Fung, Chang-Phone, Hsieh, Szu-Min, Wang, Ya-Fang, Wang, Jen-Ren, Hu, Mei-Hua, Chiang, Jen-Ron, Su, Ih-Jen, Chong, Pele Choi-Sing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836818/
https://ncbi.nlm.nih.gov/pubmed/24278177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079783
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