Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to specific receptors on the same or neighbouring cells to activate the expression of hundreds of IFN stimulated genes (ISGs) with antiviral function....

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Detalhes bibliográficos
Main Authors: Crotta, Stefania, Davidson, Sophia, Mahlakoiv, Tanel, Desmet, Christophe J., Buckwalter, Matthew R., Albert, Matthew L., Staeheli, Peter, Wack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836735/
https://ncbi.nlm.nih.gov/pubmed/24278020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003773
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