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Poliovirus replicase: a soluble enzyme able to initiate copying of poliovirus RNA.

The soluble phase of the cytoplasm of poliovirus-infected cells contains an enzymatic activity able to copy RNA without an added primer. This replicase activity has been purified 60-fold; it is absent from uninfected cells. Poly(U) polymerase activity copurifies with replicase activity. Although les...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dasgupta, A, Baron, M H, Baltimore, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/223155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2679
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