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Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals

Influenza A viruses are respiratory pathogens that cause seasonal epidemics with up to 500,000 deaths each year. Yet there are currently only two classes of antivirals licensed for treatment and drug-resistant strains are on the rise. A major challenge for the discovery of new anti-influenza agents...

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Détails bibliographiques
Auteurs principaux: Heldt, Frank S., Frensing, Timo, Pflugmacher, Antje, Gröpler, Robin, Peschel, Britta, Reichl, Udo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836700/
https://ncbi.nlm.nih.gov/pubmed/24278009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003372
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