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New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico “drug-likeness” and Pharmacokinetic Profiles

The aims of the present study were to identify the compounds responsible for the anti-malarial activity of Dacryoedes edulis (Burseraceae) and to investigate their suitability as leads for the treatment of drug resistant malaria. Five compounds were isolated from ethyl acetate and hexane extracts of...

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Detalhes bibliográficos
Main Authors: Zofou, Denis, Tematio, Esther Laure, Ntie-Kang, Fidele, Tene, Mathieu, Ngemenya, Moses N., Tane, Pierre, Titanji, Vincent P. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836662/
https://ncbi.nlm.nih.gov/pubmed/24282507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079544
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