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Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway

BACKGROUND: The Wnt pathway plays an important role in Hepatocarcinogenesis. We analyzed the association of the Wnt pathway with the proliferation of hepatoma cells using Wnt3a and niclosamide, a drug used to treat tapeworm infection. METHODS: We performed an MTS assay to determine whether Wnt3a sti...

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Detalhes bibliográficos
Main Authors: Tomizawa, Minoru, Shinozaki, Fuminobu, Motoyoshi, Yasufumi, Sugiyama, Takao, Yamamoto, Shigenori, Sueishi, Makoto, Yoshida, Takanobu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836661/
https://ncbi.nlm.nih.gov/pubmed/24273411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S50065
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