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The penetrance of ductal carcinoma in situ among BRCA1 and BRCA2 mutation carriers

Ductal carcinoma in situ (DCIS) is a precancerous lesion of the female breast and is strongly suspected to be a precursor of invasive breast cancer (IBC). Our goal is the estimation of the age-specific and lifetime penetrances of DCIS among carriers of either a BRCA1 or BRCA2 deleterious mutation. W...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mazzola, Emanuele, Cheng, Su-Chun, Parmigiani, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836600/
https://ncbi.nlm.nih.gov/pubmed/23184082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2345-5
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