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Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation

Acute pulmonary infection by Streptococcus pneumoniae is characterized by high bacterial numbers in the lung, a robust alveolar influx of polymorphonuclear cells (PMNs) and a risk of systemic spread of the bacterium. We investigated host-mediators of S. pneumoniae-induced PMN migration and the role...

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Detalhes bibliográficos
Main Authors: Bhowmick, Rudra, Maung, Nang, Hurley, Bryan P., Ghanem, Elsa Bou, Gronert, Karsten, McCormick, Beth A., Leong, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836588/
https://ncbi.nlm.nih.gov/pubmed/24089193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300522
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