Paracatalytic modification of aldolase: A side reaction of the catalytic cycle resulting in irreversible blocking of two active-site lysyl residues
Paracatalytic enzyme modifications result from the oxidation of enzyme—substrate carbanions by extrinsic oxidants. During the oxidation of enzyme-activated substrates, transiently reactive intermediates are generated which, without being released from the enzyme, modify groups at the active site. Fo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1979
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288042/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2527 |
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