2P2I(HUNTER): a tool for filtering orthosteric protein–protein interaction modulators via a dedicated support vector machine

Over the last 10 years, protein–protein interactions (PPIs) have shown increasing potential as new therapeutic targets. As a consequence, PPIs are today the most screened target class in high-throughput screening (HTS). The development of broad chemical libraries dedicated to these particular target...

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Bibliografske podrobnosti
Main Authors: Hamon, Véronique, Bourgeas, Raphael, Ducrot, Pierre, Theret, Isabelle, Xuereb, Laura, Basse, Marie Jeanne, Brunel, Jean Michel, Combes, Sebastien, Morelli, Xavier, Roche, Philippe
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2014
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836326/
https://ncbi.nlm.nih.gov/pubmed/24196694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.0860
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