Translational Studies of Phenotypic Probes for the Mononuclear Phagocyte System and Liposomal Pharmacology

As nanoparticles (NPs) are cleared via phagocytes of the mononuclear phagocyte system (MPS), we hypothesized that the function of circulating monocytes and dendritic cells (MO/DC) in blood can predict NP clearance (CL). We measured MO/DC phagocytosis and reactive oxygen species (ROS) production in m...

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Main Authors: Caron, Whitney P., Lay, John C., Fong, Alan M., La-Beck, Ninh M., Kumar, Parag, Newman, Suzanne E., Zhou, Haibo, Monaco, Jane H., Clarke-Pearson, Daniel L., Brewster, Wendy R., Van Le, Linda, Bae-Jump, Victoria L., Gehrig, Paola A., Zamboni, William C.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
Fag:
Chemotherapy, Antibiotics, and Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836305/
https://ncbi.nlm.nih.gov/pubmed/24042160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208801
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