Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

The opioid system is implicated in the hedonic and motivational processing of food, and in binge eating, a behaviour strongly linked to obesity. The aim of this study was to evaluate the effects of 4 weeks of treatment with the mu-opioid receptor antagonist GSK1521498 on eating behaviour in binge-ea...

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Autors principals: Ziauddeen, H, Chamberlain, S R, Nathan, P J, Koch, A, Maltby, K, Bush, M, Tao, W X, Napolitano, A, Skeggs, A L, Brooke, A C, Cheke, L, Clayton, N S, Sadaf Farooqi, I, O'Rahilly, S, Waterworth, D, Song, K, Hosking, L, Richards, D B, Fletcher, P C, Bullmore, E T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835938/
https://ncbi.nlm.nih.gov/pubmed/23147384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.154
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