Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth

BACKGROUND: Regulation of lipid metabolism via activation of sterol regulatory element binding proteins (SREBPs) has emerged as an important function of the Akt/mTORC1 signaling axis. Although the contribution of dysregulated Akt/mTORC1 signaling to cancer has been investigated extensively and alter...

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Autori principali: Griffiths, Beatrice, Lewis, Caroline A, Bensaad, Karim, Ros, Susana, Zhang, Qifeng, Ferber, Emma C, Konisti, Sofia, Peck, Barrie, Miess, Heike, East, Philip, Wakelam, Michael, Harris, Adrian L, Schulze, Almut
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835903/
https://ncbi.nlm.nih.gov/pubmed/24280005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-3
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