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Targeting TNF-α and NF-κB Activation by Bee Venom: Role in Suppressing Adjuvant Induced Arthritis and Methotrexate Hepatotoxicity in Rats

Low dose methotrexate is the cornerstone for the treatment of rheumatoid arthritis. One of its major drawbacks is hepatotoxicity, resulting in poor compliance of therapy. Dissatisfied arthritis patients are likely to seek the option of complementary and alternative medicine such as bee venom. The co...

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Detalhes bibliográficos
Main Authors: Darwish, Samar F., El-Bakly, Wesam M., Arafa, Hossam M., El-Demerdash, Ebtehal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835890/
https://ncbi.nlm.nih.gov/pubmed/24278124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079284
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