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Evaluation of Paeonol Skin-Target Delivery from Its Microsponge Formulation: In Vitro Skin Permeation and In Vivo Microdialysis

The aim of the present study was to design a novel topical skin-target drug-delivery system, the paeonol microsponge, and to investigate its drug-release patterns in dosage form, both in vitro and in vivo. Paeonol microsponges were prepared using the quasi-emulsion solvent-diffusion method. In vitro...

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Detalhes bibliográficos
Main Authors: Li, Sha-Sha, Li, Guo-Feng, Liu, Li, Jiang, Xiao, Zhang, Bin, Liu, Zhi-Gang, Li, Xue-Ling, Weng, Li-Dong, Zuo, Ting, Liu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835837/
https://ncbi.nlm.nih.gov/pubmed/24278204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079881
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