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Kinetic Mechanism of Human Histidine Triad Nucleotide Binding Protein 1 (Hint1)

Human histidine triad nucleotide binding protein 1 (hHint1) is a member of a ubiquitous and ancient branch of the histidine triad (HIT) protein superfamily. hHint1 is a homodimeric protein that catalyzes the hydrolysis of model substrates, phosphoramidate (TpAd) and acyl adenylate (AIPA), with a hig...

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Bibliographic Details
Main Authors: Zhou, Xin, Chou, Tsui-Fen, Aubol, Brandon E, Park, Chin Ju, Wolfenden, Richard, Adams, Joseph, Wagner, Carston R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835729/
https://ncbi.nlm.nih.gov/pubmed/23614568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301616c
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