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Current approaches and future directions in the treatment of HER2-positive breast cancer
Human epidermal growth factor receptor 2 (HER2), a member of the ErbB family of transmembrane receptor tyrosine kinases, is amplified in 20–30% of invasive breast cancers. HER2 amplification is associated with metastasis and reduced survival. Two HER2-directed therapies have been approved by the Uni...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835685/ https://ncbi.nlm.nih.gov/pubmed/22658319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2012.04.008 |
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