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Synthesis and use of 8-azidoguanosine 3',5'-cyclic monophosphate as photoaffinity label for cyclic GMP-dependent protein kinase.

8-Azidoguanosine 3',5'-cyclic monophosphate (8-N3cGMP) has been synthesized for use as a photoactive probe for the labeling of cGMP receptors. The ability of 8-N3cGMP to be bound at specific cGMP binding sites was demonstrated by its ability to activate cGMP-dependent protein kinase isolat...

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Detalhes bibliográficos
Main Authors: Geahlen, R L, Haley, B E, Krebs, E G
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383568/
https://ncbi.nlm.nih.gov/pubmed/221918
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