Microtubules Underlie Dysfunction in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked degenerative muscle disease caused by the absence of the microtubule-associated protein dystrophin, which results in a disorganized and denser microtubule cytoskeleton. In addition, mechanotransduction-dependent activation of calcium (Ca(2+)) and...

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Hlavní autoři: Khairallah, Ramzi J., Shi, Guoli, Sbrana, Francesca, Prosser, Benjamin L., Borroto, Carlos, Mazaitis, Mark J., Hoffman, Eric P., Mahurkar, Anup, Sachs, Fredrick, Sun, Yezhou, Chen, Yi-Wen, Raiteri, Roberto, Lederer, W. Jonathan, Dorsey, Susan G., Ward, Christopher W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835660/
https://ncbi.nlm.nih.gov/pubmed/22871609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002829
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