Impaired Natriuretic and Renal Endocrine Response to Acute Volume Expansion in Pre-Clinical Systolic and Diastolic Dysfunction

OBJECTIVES: We hypothesized an impaired renal endocrine and natriuretic response to volume expansion (VE) in humans with pre-clinical systolic dysfunction (PSD) and pre-clinical diastolic dysfunction (PDD). We further hypothesized that exogenous B-type natriuretic peptide (BNP) could rescue an impai...

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Autori principali: McKie, Paul M., Schirger, John A., Costello-Boerrigter, Lisa C., Benike, Sherry L., Harstad, Lynn K., Bailey, Kent R., Hodge, David O., Redfield, Margaret M., Simari, Robert D., Burnett, John C., Chen, Horng H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835631/
https://ncbi.nlm.nih.gov/pubmed/22051332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.07.042
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