Chemoresistance to Concanamycin A1 in Human Oral Squamous Cell Carcinoma Is Attenuated by an HDAC Inhibitor Partly via Suppression of Bcl-2 Expression

V-ATPase is involved in the acidification of the microenvironment around/in solid tumors, such as oral squamous cell carcinoma (OSCC). V-ATPase is thought to induce tumor invasion and multi-drug resistance in several malignant tumors, and it also contributes to maintaining the intracellular pH under...

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Detalhes bibliográficos
Main Authors: Kiyoshima, Tamotsu, Yoshida, Hisato, Wada, Hiroko, Nagata, Kengo, Fujiwara, Hiroaki, Kihara, Makiko, Hasegawa, Kana, Someya, Hirotaka, Sakai, Hidetaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835574/
https://ncbi.nlm.nih.gov/pubmed/24278362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080998
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