Low-dose nesiritide in human anterior myocardial infarction suppresses aldosterone and preserves ventricular function and structure: a proof of concept study

BACKGROUND: B-type natriuretic peptide (BNP, nesiritide) has anti-fibrotic, anti-hypertrophic, anti-inflammatory, vasodilating, lusitropic and aldosterone-inhibiting properties but conventional doses of BNP cause hypotension, limiting its use in heart failure. OBJECTIVE: To determine whether infusio...

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Detalhes bibliográficos
Main Authors: Chen, H H, Martin, F L, Gibbons, R J, Schirger, J A, Wright, R S, Schears, R M, Redfield, M M, Simari, R D, Lerman, A, Cataliotti, A, Burnett, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835541/
https://ncbi.nlm.nih.gov/pubmed/19447837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2008.153916
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