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Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors

Marine-derived fungi have proven to be important sources of bioactive natural organohalides. The genus Penicillium is recognized as a rich source of chemically diverse bioactive secondary metabolites. This study reports the fermentation, isolation and identification of a marine-derived Penicillium s...

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Detalhes bibliográficos
Main Authors: Sallam, Asmaa A., Houssen, Wael E., Gissendanner, Chris R., Orabi, Khaled Y., Foudah, Ahmed I., El Sayed, Khalid A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835464/
https://ncbi.nlm.nih.gov/pubmed/24273638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00198A
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